Kev tshawb fawb tshiab Aims kom txhob Biological lub sij hawm, pab rau cov tos

LifeSource Zoo siab txhawb lub inaugural launch txog lub koom haum Biostasis kev tshawb fawb lub koom haum, tswj eliminating cia txwv rau organs, ntaub so ntswg thiab lwm yam loj biological lub nruab. Teg num no aims txo sij hawm rau daim ntawv tos yav tom ntej transplant cov neeg tau txais kev pab thiab tso cai rau ntau lwm tus ua organ hloov – ib lub caij nyoog tsawg tsawg vim tam sim no. Qhov no zoo kawg ua hauj lwm yuav ua ntej qhov LifeSource Lub hom phiaj los tsim lub heroism ntawm txhua lub txiv kab ntxwv hloov los maximizing tej yam ntawm lawv lub neej-txuag khoom plig.

Tom qab xyoo lawm ntawm kev tshawb fawb, cov Biostasis kev tshawb fawb lub koom haum yuav activate ob academic centers nplooj siab rau lub cryopreservation ntawm cov txiv kab ntxwv thiab cov nqaij mos – ib tug thawj hauv Teb Chaws Asmeskas keeb kwm. No av-rhuav kev tshawb fawb yog zoj zis xwb ob peb mais ntawm LifeSource ntawm lub tsev kawm ntawv ntawm lub tsev kawm ntawv Minnesota.

Qab lub Innovation: Cryogenic Cia ntawm Organs

Lub txiv kab ntxwv thiab cov ntaub so ntswg Preservation Center yuav tsom rua kev ruaj ntseg thiab ceev rewarm cryopre txais kev pab thiab lwm lub nruab nrog cev.

Qhov chaw no yog tsev nyob rau hauv lub tsev kawm ntawv ntawm Minnesota Lub koom haum rau Engineering hauv tshuaj (IEM) thiab yuav tau coj los ntawm tus IEM Director, Dr. John Bischof, thiab Department of Phais faculty neeg, Dr. Erik Finger.

Txoj kev yuav cia organs yuav muab cia rau hauv ib cov kua nitrogen freezer rau hnub los txawm tias xyoo. Qhov kub freezer kub, lub sij hawm ntev lub sij hawm. Ntawm no yog li cas nws ua haujlwm:

• LifeSource koom tes nrog tsev neeg uas tau xaiv los koom rau hauv txoj kev tshawb fawb.
• Lub U.S. pab neeg ntxiv biological los tiv thaiv molecules rau lub txiv kab ntxwv, thiab ces lawv txo qhov kub hauv tej ib txoj kev uas lub txiv kab ntxwv yuav tsis crystalize. Thaum lub txiv kab ntxwv muab tso rau hauv ib khob iav, cov metabolism yeej tseem zoo nres. Zoo, preserving lub kaw lus biological indefinitely.
• Thaum npaj siv, lub txiv kab ntxwv yog rewarmed thiab reanimated.

No kauj ruam kawg ntawm rewarming thiab reanimating lub txiv kab ntxwv tom qab khov lawm ib tug sib tw loj. Piv txwv li, yog ib lub txiv kab ntxwv khov yog reheated sai heev los yog unevenly, nws yuav tawg. Lub tsev kawm ntawv ntawm lub tsev kawm ntawv Minnesota Pab neeg no tau tsim txoj kev tshiab thiab tshuab uas yog uas qhia cog lus rau fixing cov teeb meem no. Ib txoj kev yog profuse lub txiv kab ntxwv nrog hlau oxide nanoparticles, uas yog reactivated ces uniformly thiab ceev rov qab mus rau lub txiv kab ntxwv kom tag nrho.

Lub sij hawm tam sim no timeframe rau Preserving thiab Transplanting Organs?

Txhua xyoo, roughly 3,500 raum thiab 3,000 livers ntawm Teb Chaws Asmeskas hloov tsis tau matched rau ib tug neeg txais kev pab ua ntej lawv preservation txwv expires, nrog rau ntau lub siab lub ntsws, ntsws, thiab pancreata.

Tam sim no, txhua lub txiv kab ntxwv muaj ib lub sij hawm specific timeframe uas cov transplant yuav tsum tshwm sim thaum lub donation yog zoo tu qab tso:

• Plawv: 4 – 6 teev
• Ntsws: 4-8 teev
• Nplooj Siab: 8 – 12 teev

• Pancreas: 12 – 18 teev
• Hnyuv Mos: 8 – 16 teev
• Raum: 24 – 36 teev

Biostasis muaj tej zaum mus cuag matching hnub los yog lub lis piam tsis txhob teev. Qhov no yuav tau tshem cov hurdle ntawm geography, tsim muaj peev xwm muab organs nyob deb li cas, eliminating qhov uas yuav ncua los yog lawm os flights los yog kev khiav hauj lwm chav tsev.

Li cas yuav qhov kev tshawb fawb tej yam neeg tam sim no tos ib lub neej-txuag Transplant?

Txuag lub neej yog ib txwm qhov tseem ceeb tshaj plaws. Yog hais tias ib tug neeg lub txiv kab ntxwv yog suitable rau transplant, peb yuav tsum, thiab peb yuav, nrhiav ib tug neeg mob yuav tau txais cov transplant. Tab sis ntau zaus, yog transplant tsis tau, kev tshawb fawb no tej zaum yuav tau.

Thaum tib neeg pub, lawv yuav pab tau ib tug neeg uas muaj cov khoom plig ntawm lub neej tam sim no, tiam sis kuj yog lub sijhawm los pab ib tug neeg yav tom ntej los ntawm kev tshawb fawb yog transplant tsis tau. Lub U.S. paab npaj pib kuaj lawv rau pub tib neeg organs uas tsis tau transplanted tom qab lub caij ntuj sov no (2021).

"Nws yuav ua tau ib qhov zoo kawg li kev ua si-changer, tsis zoo xwb nyob rau lub sij hawm xwb, tiam sis kuj tau nrhiav tau tias zoo meej match, qhov zoo tshaj plaws rau tus neeg mob," LifeSource CEO Susan Gunderson hais. "Rau cov me nyuam particular, peb yeej sib tw nrog nrhiav txoj cai loj match organ thaum lub sij hawm ib tug neeg mob xav tau nws. Uas yog ntsoog loj heev. Kuv xav tias qhov no theem comfort rau cov neeg uas tos ib transplant hnub no paub tias cov kev kawm tseem tsim. Nws yog ib tug cog lus ntawm vam cia."