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Run/walk to save lives and honor donors, Oct. 18!

Organ donation is a generous, selfless gift

LifeSource is honored to fulfill the decision of people in our community to save lives through tissue and organ donation. Families like The Yangs found healing knowing their son saved lives and helped others.

One of 55 Organ Procurement Organizations (OPOs) in the country, we serve the second largest geographical region, focusing on Minnesota, North Dakota, South Dakota and portions of western Wisconsin.

Tony and Pricilla Yang
Why Donation Matters

Eye, tissue and organ donation offers healing to a family experiencing a loss and hope to the patient receiving the transplant.

  • 13 People die each day waiting for an organ transplant
  • 75 1 donor can heal more than 75 lives through eye and tissue donation
  • 8 1 donor can save up to 8 lives through organ donation

How organ donation works

The organ donation process has been described as symphony; it takes many people working in concert to make the complex process happen.

Our Work

We save lives through donation and offer hope and healing

Organ Procurement Organizations (OPOs) are the vital bridge between donors, their families and potential recipients.

At LifeSource, we have a clear purpose – to inspire the public to register and work with all of our partners to support donor families, manage the donation process, transport the gifts to the transplant center and lead our communities towards a culture of donation. 

Child and Butterfly

The latest from LifeSource

Check out the latest updates, news, stories and more.

  • July 18, 2025 in Stories

    A dance between grief and gratitude: What I learned about organ donation after my husband’s sudden death

    When Christopher passed away unexpectedly, his wife Sarah was faced with impossible grief — and a life-changing decision. In this deeply moving personal testimonial, she shares what it was like to say yes to organ donation in the midst of heartbreak.

    Read More
  • July 17, 2025 in About Donation, Our Experts

    Organ donation after circulatory death (DCD): What it means, how it happens and why it matters

    You may already know that people can donate organs after they die — but did you know two different pathways can happen? One of those ways is called Donation after Circulatory Death (DCD).

    Read More
  • June 27, 2025 in Community

    Men’s Health Month: Clarence Jones on health, community and organ donation

    June is Men’s Health Month — a time to raise awareness about the importance of preventive care and healthy living for men. For longtime advocate and LifeSource partner, Clarence Jones, men’s health is deeply connected to his work in organ donation and his passion for community wellness.

    Read More
  • June 26, 2025 in Community, Stories

    Trails4Transplant: Saddle up to raise awareness for organ donation

    Each year, a special group of riders and volunteers gather on horseback, united by a mission to spread hope, healing, and the importance of registering as an organ, eye and tissue donor.

    Read More
  • June 04, 2025 in About Donation, Our Experts

    Will doctors try as hard to save me if I’m an organ donor?

    Worried that being an organ donor might affect the medical care you get in an emergency? You’re not alone. Here’s the truth — directly from the experts.

    Read More
Public Awareness Campaign

Busting myths,
saving lives!

Only about 50% of people in the Upper Midwest have registered as organ donors, and many misconceptions are contributing to people on the transplant waiting list not being able to get the organ they need. Our latest public awareness campaign features Bigfoot – one of the greatest legends of all time – busting myths and highlighting the truth about the importance of donation. Organ donation is for the big at heart, so let’s work together to reduce the waiting list and save lives.

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